By George M. Rodgers
This finished quantity discusses the protease ADAMTS13, summarizing the present prestige of easy and medical study. The 9 authoritative chapters start with a ancient standpoint via exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its common functionality in hemostasis (cleavage of von Willebrand factor). rising learn issues for ADAMTS13 are coated, together with its strength function in angiogenesis and different points of mobile biology. extra themes comprise laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and bought ADAMTS13 deficiency. A bankruptcy on similar thrombotic microangiopathic (TMA) problems examines the diversities among TMAs linked to ADAMTS13 deficiency and people now not linked to ADAMTS13 deficiency. a last bankruptcy reports the initial info on rising points of ADAMTS13, akin to the prestige of recombinant ADAMTS13 items and their capability utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and illness is an important source for scientific hematologists, transfusion drugs physicians, and researchers drawn to hemostasis, vascular biology, biochemistry, and metalloproteases.
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